THE COMPARISON OF SUMATERA FOREST HONEY AND TRIAMCINOLONE ACETONIDE FOR TRAUMATIC ULCER HEALING IN WISTAR RAT: CLINICAL AND HISTOLOGICAL EVALUATION

Received 2024-03-01; Accepted 2024-03-13; Published 2024-03-27

Authors

  • Aida Fadhilla Darwis Department of Oral Medicine, Faculty of Dentistry, Universitas Sumatera Utara.
  • Armia Syahputra Department of Periodontology, Faculty of Dentistry, University Sumatra Utara.
  • Erliera Sufarnap Department of Orthodontology, Faculty of Dentistry, Universitas Sumatera Utara.
  • Elfriza Wilda Sari Harahap Profession Student, Faculty of Dentistry, University Sumatra Utara, Alumni Street No. 2, Medan Baru 20222, Medan, Indonesia.

DOI:

https://doi.org/10.22452/jummec.sp2024no1.33

Abstract

Traumatic ulcer is ulcerated lesion on oral mucosa commonly caused by mechanical injury. The clinical picture of a traumatic ulcer is a solitary ulcer, it can be oval or irregular in shape, the center of the ulcer is yellow-gray or white/grey with erythematous edges. Traumatic ulcer cause difficulty in mastication, speech, and swallowing. Forest honey is a traditional medicine that can be used to heal traumatic wounds because of its anti-inflammatory, antimicrobial, antioxidant, and covering agent.  The purpose of this study was to determine the effectiveness of Sumatera Forest honey on healing of traumatic ulcer in Wistar rats. This study is a quasi-experimental study. This study involved 32 rats divided into two groups, each containing 16 rats, namely the treatment group (100% forest honey) and the control group (Triamcinolone Acetonide). The animal model was slashed with a scalpel to induce an ulcer. The data collection was done by examining the size of the ulcer and erythema and then observed on the 1, 5, 7, 10 and 14 days. Analysis in this study used the Mann Whitney and Cochran statistical test. The results showed that Sumatera-forest honey significantly reduce ulcer size (p = 0.001) and erythema (p = 0.000). Sumatera forest honey is effective in healing traumatic ulcer.

Downloads

Download data is not yet available.

Downloads

Published

2024-03-27

Issue

Special Issue 1 (2024)

Section

Research article

License

All authors agree that the article, if editorially accepted for publication, shall be licensed under the Creative Commons Attribution License 4.0 to allow others to freely access, copy and use research provided the author is correctly attributed, unless otherwise stated. All articles are available online without charge or other barriers to access. However, anyone wishing to reproduce large quantities of an article (250+) should inform the publisher. Any opinion expressed in the articles are those of the authors and do not reflect that of the University of Malaya, 50603 Kuala Lumpur, Malaysia.