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Introduction: Schizencephaly is a rare congenital malformation of cerebral cortical development. Epilepsia partialis continua and movement disorders often display abnormal movements with overlapping phenomenology in schizencephaly. Case report: A 6-year-old-girl with normal prenatal and labor history, presented with continuous left hand movement since 1-year-old. Neurological examination showed left spastic hemiparesis. Electroencephalography (EEG) showed sharp and spike wave in right temporoparietooccipital, frontocentrotemporal and centroparietal region. Cerebral magnetic resonance imaging (MRI) showed a cleft in right frontal lobe extending to the right lateral ventricle classified as open-lip schizencephaly, and an agenesis of septum pellucidum leads to monoventricular features, and polymicrogyria. She was treated with valproic acid, haloperidol, and regular physiotherapy. Conclusion: This patient was diagnosed with schizencephaly from the anamnesis, physical examination, EEG, and cerebral MRI. The therapy of this patient was pharmacological treatment and physiotherapy.
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