Changes In Serum Proteins, Erthrocyte Sedimentation Rate And Mantoux Tuberculin Skin Test Reactivity In Active Tuberculosis

Authors

  • Liam Chong Kin
  • Lim Kim Hatt
  • Catherine Wong Mee Ming

Abstract

The records of 141 consecutive patients with proven tuberculosis (TB) were reviewed to examine for changes in their serum proteins, erythrocyte sedimentation rate (ESR) and tuberculin skin test reactivity. Hypoalbuminaernia was present in 73% of patients and hyperglobulinaentia was seen in 92% of patients. ESR showed a negative correlation with the serum albumin level but a positive correlation with the serum globulin level. In the case of pulmonary TB, ESR was higher in patients with radiologically more extensive disease. Tuberculin reactivity was reduced in patients who were older, those with more severe Iiypoalbuininaemia and those with disseminated TB.

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Published

1998-12-28

Issue

Section

Research article